职 称：讲师
学 历：博士
E-mail: zhouhong@hbut.edu.cn
研究方向：情绪情感类精神障碍发病机制；表观遗传
学习、工作经历：
2009.9-2013.6 华中师范大学 生命科学学院 生物技术专业 学士
2013.6-2015.6 武汉大学 生命科学学院 遗传学 硕士
2015.9-2018.6 武汉大学生命科学学院遗传学博士
2018.9-2023.2 华中科技大学基础医学院博士后
2023.3至今 湖北工业大学讲师
研究课题：
1.项目“GM527蛋白通过影响多巴胺受体引起精神分裂症相关表型的机理”，No. 82071508；国家自然科学基金面上项目，参与。
2.项目“海马记忆痕迹的消除及其动态调节”，No.31970961，湖北省自然科学基金重点项目，参与。
研究成果：
1.Hong Zhou#,Jiayu Zhu#, Jie Jia, Wei Xiang, Hualing Peng, Yuejin Zhang, Bo Liu*, Yangling Mu*, Yisheng Lu*. The antidepressant effect of nucleus accumbens deep brain stimulation is mediated by parvalbumin-positive interneurons in the dorsal dentate gyrus. Neurobiology of stress. 2022,21:100492. (IF: 7.146)
2.Hong Zhou†, Wei Xiang†, Mengbing Huang*. Inactivation of zona incerta blocks social conditioned place aversion and modulates post-traumatic stress disorder-like behaviors in mice.Frontiers in Behavioral Neuroscience. 2021 Oct 21;15:743484. ( IF: 3.617）
3. Hong Zhou†, Yapei Wang†, Qing Wang, Yan Hu, Hao Zhang, Xueke Zheng, Haoli Hou, Li L*. Rloops mediate transcription-associated formation of human rDNA secondary constrictions. Journal of Cellular Biochemistry, 2021;1-17. (IF:4.48)
4.Hong Zhou †, Le Li†, Qing Wang †, Yan Hu, Weiwei Zhao, Mayank Gautam, Lijia Li*. H3K9 demethylation-induced R-loop accumulation is linked to disorganized nucleoli. Frontiers in Genetics, 2020, 11:43. ( IF: 4.77)
5. Hong Zhou, Yapei Wang, Qiongying Lu, Juan Zhang, Qing Wang, Fei Gao, Haoli Hou, Hao Zhang, Wei Zhang *, Lijia Li*. Overexpression of ribosomal RNA in the development of human cervical cancer is associated with rDNA promoter hypomethylation. Plos One, 2016, 11(10): e0163340. (IF: 3.75)
6. Fei Gao, Ningjie Ma, Hong Zhou, Qing Wang, Hao Zhang, Pu Wang, Haoli Hou, Huan Wen, LijiaLi*. Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytes. International Journal of Nanomedicine, 2016,11: 3859–3874. (IF: 6.4)
7. Qing Wang, Pu Wang, Hong Zhou, Yan Hu, Chengshen Xie, Fei Gao, Ningjie Ma, Haoli Hou, Hao Zhang, Lijia Li*. 5-Azacytidine specifically inhibits the NIH-3T3 PCD process induced by TNFalpha and cycloheximide via affecting BCL-XL. Journal of Cellular Biochemistry, 2017,08: 1-10.
8. Haoli Hou, Xueke Zheng, Hao Zhang, Mengxia Yue, Yan Hu, Hong Zhou, Qing Wang, ChengshenXie, Pu Wang, Li L*. Histone deacetylase is required for GA-induced programmed cell death in maize aleurone layers. Plant Physiology, 2017, 9(27). (IF:8.43)
